Marjon Borgert

183 Implementation of a transfusion bundle ●● ●●●● ● ● ●● ●●● ● ●●●●● ●●●●● ●● ●● ● ● ● ● ● ●● ●● ● ●● ● ●● ● ● ● ● ● ● ● ●●●●● ● ●●●●●●●●●●● ● ● ● ● ● ●● ● ● ● ●●●● ● ●●● ●●● ● ● ● ● ● ● ●● ● ● ●● ● ● ● ●●●●●●●●● ● ● ● ● ● ● ● ● ●● ● ● ●●● ● ● ●● ● ● ●●● ● ● ● ● ●● ● ● ●● ● ●● ● ● ● ● ● ● ● ● ●● ●● ● ● ●● ● ● ● ● ●● ● ●● ● ● ● ● ● ● ● ●● ● ● ● ●●●● ● ● ●●●● ●● ● ● ●●● ● ●●●● ● ● ●● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ●●● ●●●●● ●●●●●● ●●●●●●●●●●●●●● ● ● ● ●● ●● ● ● ●●● ● ●● ● ●●● ● ● ●● ● ●●● ●● ●●● ●● ●● ● ● ●●● ● ● ● ●● ●● ●● ● ●●● ●● ● ●● ● ● ● ● ● ● ●●● ●● ● ●●● ● ● ● ● ● ● ● ● ●● ● ● ●● ● ● ● ● ● ●● ● ● ●● ●● ● ● ●●● ●● ● ● ●● ● ● ● ●● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ●●● ● ● ● ● ●● ● ● ●● ●● ● ● ● ● ● ● ●● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ●●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ●● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ●● Baseline Phase 1 Phase 2 3 6 9 0 100 200 300 Year day 1 to 365 in 2014 Hb (g/dL) reference level (lightgrey) and pre transfusion levels (darkgrey) Figure 1. Patients’ individual pre-set Hb threshold as green dots and pre-transfusion Hb level as blue dots Hb (g/dL) reference level (green) and pre transfusion levels (blue)

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