Marjon Borgert

69 A flowchart for building evidence-based care bundles RESULTS In total, 4665 articles were identi ed for possible inclusion through the initial search (Fig. 1). After screening titles and abstract, 107 full-text articles were reviewed. A nal set of 18 articles met the inclusion criteria and were included in this study. Figure 1. Flowchart of the study selection procedure Study characteristics The development of the ventilator bundle was reported in 17% (3/18) and for central line placement as well as for prescribing antibiotics in 11% (2/18). The remaining studies reported the methods used for the following bundles: sepsis; cerebral ventricular drainage; ventriculostomy placement; palliative care; thirst intensity and thirst distress (Table 1). In 33% (6/18), the whole bundle design process was reported. In 50% (9/18),