Peter van Mourik

158 Chapter 7 Supplemental Figure S2. Correlation between individual in vitro organoid response and in vivo change in ppFEV 1 and SCC, controlled for repeated measurements. (a,b) Correlations between response of the organoids of an individual patient upon CFTR modulating treatment in combination with 0.128 μM Forskolin and the in vivo response (change in ppFEV 1 and change in SCC) of the same patient to the same treatment for patients who had a ppFEV 1 ≥40% and ≤90% before the start of treatment, controlled for repeated measurements.