Ingrid 't Hart

Table of contents Chapter 1 7 Introduction Chapter 2 27 Chemoenzymatic synthesis of the oligosaccharide moiety of the tumor-associated antigen disialosyl globopentaosylceramide Chapter 3 55 Chemical and chemoenzymatic synthesis of globo-series glycosphingolipids (GSLs) Chapter 4 75 Chemical synthesis of an O-glycan analog of sulfoglycolipid SM1a: SM1-core3 A potential glycan antigen for cancer-specific monoclonal antibody HAE3 Chapter 5 95 Chemoenzymatic synthesis of C. jejuni heptose-ganglioside mimics to study antibody binding patterns in Guillain-Barré Syndrome Chapter 6 107 Summary/Samenvatting Appendices 117 Curriculum Vitae List of Publications Acknowledgements