Fehmi Keçe

Chapter 6 132 time-to-isolation, minimum balloon temperature, warming time and minimum esophageal temperature between the three groups. Single-shot isolation was achieved in respectively 81, 79 and 72% of the PVs in the 90, 120 and 150s (p=0.254). There were no significant differences in single-shot isolation rates between the PVs (76% for the left superior PV, 81% for the left inferior PV, 82% for the right superior PV and 72% for the right inferior PV, p=0.465). Table 2: Procedural details. 90s (n=25) 120s (n=25) 150s (n=25) P value Procedure Time (min 138±32 118±26 126±31 0.053 Total cryoapplication time (min) 18±6 15±4 17±4 0.132 Balloon size (28 mm) 24 (96) 23 (92) 23 (92) 1.000 Balloon size (23 mm) 1 (4) 1 (4) 2 (8) 1.000 Ballloon size (23 and 28 mm) 0 1 (4) 0 1.000 Fluroscopy time (min) 24±11 19±9 23±12 0.296 Dose-area product (mSV) 2.4±1.5 1.9±1.0 2.8±2.1 0.184 Cavotricuspid isthmus ablation 7(28) 4(16) 4(16) 0.472 Mean time-to-isolation (s) 51±25 49±26 52±27 0.641 Mean cryo-application time (s) 146±28 167±30 192±34 <0.001 Warming Time (s) 40±18 41±20 39±19 0.836 Min. balloon Temperature (°C) -43±7 -45±7 -45±7 0.038 Min. oesophageal temperature (°C) 34±5 32±6 33±6 0.249 Values are reported as the mean±standard deviation or n (%). 6.3.3 PV reconnection/DC The numbers of patients and PVs with reconnection/DC are specified in Table 3. A significant decrease in reconnection/DC and a corresponding decrease in the number of additional cryo-applications was shown with increasing ablation durations. The procedural duration was also prolonged by the additional applications to abolish dormant conduction and an additional waiting-period of 30 minutes. 6.3.4 Predictors of PV reconnection/DC In multivariate analysis, a shorter cryo-application time, longer time-to-isolation, a higher nadir balloon temperature and more unsuccessful ablations were associated with a higher incidence of PV reconnection/DC (Table 4). Warming time was not a significant predictor in multivariate analysis.