Fehmi Keçe

Chapter 7 150 Table 3. Biophysical parameters. No ERC (522) ERC (n=53) P value Temperature at 30 seconds (°C) -31±5 -29±8 0.058 Temperature at 60 seconds (°C) -39±6 -35±8 0.004 Nadir Balloon Temperature (°C) -47±7 -42±9 <0.001 Temperature at time-to-isolation (°C) -34±8 -34±8 0.789 Freeze (AUC) 7999±7285 7285±1961 0.007 Freeze magnitude (Freeze AUC/total application time) 38±5 35±7 <0.001 Warming time to 0 °C (s) 9±6 6±4 0.001 Warming time to 15 °C (s) 35±16 25±16 <0.001 Warming time to 20 °C (s) 42±18 31±18 <0.001 AUC=Area-under-the-curve (sum of temperature x time) Table 4. Biophysical and procedural predictors for early reconnection/dormant conduction. Variables Univariable Multivariable Odds ratio (95% confidence interval) P value Odds ratio (95% confidence interval) P value Procedural Time to isolation 1.0 [1.01-1.03] <0.001 1.1 [1.01 – 1.03] 0.001 Number of Unsuccessful freezes 1.5 [1.18-2.01] <0.001 1.7 [1.15 – 2.49] 0.008 Biophysical Temperature at 30 seconds 1.1 [1.02 – 1.13] 0.006 0.9 [0.82-1.0] 0.057 Temperature at 60 seconds 1.1 [1.05 – 1.17] <0.001 Nadir Temperature 1.1 [1.06-1.15] <0.001 1.2 [1.09 – 1.23] <0.001 Temperature at time-to-isolation 1.0 [0.95 – 1.04] 0.885 Freeze (area under the curve) 1.0 [1.0 – 1.0] 0.008 Freeze magnitude 0.9 [0.83 – 0.93] <0.001 Warming time to 0 0.9 [0.78-0.93] <0.001 Warming time to 15 1.0 [0.94-0.98] <0.001 Warming time to 20 1.0 [0.95-0.98] <0.001