Fehmi Keçe

Predicting Early Reconnection with Procedural and Biophysical Parameters 151 7 In figure 1, a ROC-curve is constructed with the three available parameters with an area under the curve of 0.75. Based on the coefficients, 0.02, 0.5 and 0.2 for respectively time-to-isolation, number of unsuccessful freezes and nadir balloon temperature, a combined cut-of-value of ≥-6.7 was calculated to predict ERC with a 86% specificity and 70% sensitivity. By applying the derived formula on different values of the respective parameters, we constructed table 5 for clinical decision making to either apply a waiting period with adenosine testing (ERC testing) or to refrain from it. Area under ROC curve = 0.752 Figure 1. ROC curve predicting early reconnection/dormant conduction using the three parameters. 7.3.6 Acute complications and follow-up In 2 patients, groin-related complications (1.3%) and in 4 patients, phrenic nerve palsy persisting after one year (2.6%) occurred. The one-year off anti-arrhythmic drug AF-free survival in the total group was 69% and was not significantly different between the two groups (68% vs. 71%, p=0.983). Eleven patients were lost to follow up.