Fehmi Keçe

Chapter 7 156 Tabel 5. Cut-off-values for time-to-isolation to predict early reconnection/dormant conduction. Unsuccessful freezes (n) 0 1 2 3 Balloon temperature (°C) Time-to-isolation (s) Time-to-isolation (s) Time-to-isolation (s) Time-to-isolation (s) -30 ERC test ERC test ERC test ERC test -31 ERC test ERC test ERC test ERC test -32 ERC test ERC test ERC test ERC test -33 ERC test ERC test ERC test ERC test -34 ≥5: ERC test ERC test ERC test ERC test -35 ≥15: ERC test ERC test ERC test ERC test -36 ≥25: ERC test ERC test ERC test ERC test -37 ≥35: ERC test ≥10: ERC test ERC test ERC test -38 ≥45: ERC test ≥20: ERC test ERC test ERC test -39 ≥55: ERC test ≥30: ERC test ≥5: ERC test ERC test -40 ≥65: ERC test ≥40: ERC test ≥15: ERC test ERC test -41 ≥75: ERC test ≥50: ERC test ≥25: ERC test ERC test -42 ≥85: ERC test ≥60: ERC test ≥35: ERC test ≥10: ERC test -43 ≥95: ERC test ≥70: ERC test ≥45: ERC test ≥20: ERC test -44 NO ERC test ≥80:ERC test ≥55: ERC test ≥30: ERC test -45 NO ERC test ≥90: ERC test ≥65: ERC test ≥40: ERC test -46 NO ERC test NO ERC test ≥75: ERC test ≥50: ERC test -47 NO ERC test NO ERC test ≥85: ERC test ≥60: ERC test -48 NO ERC test NO ERC test ≥95: ERC test ≥70: ERC test -49 NO ERC test NO ERC test NO ERC test ≥80:ERC test -50 NO ERC test NO ERC test NO ERC test ≥90: ERC test Based on the coefficients a formula is created for the three significant parameters (0.02* time-to- isolation + 0.5 * number of unsuccessful freezes and 0.2* nadir balloon temperature). With a 86% specificity and 70% sensitivity a combined cut-off-value of-6.7 is predictive for early reconnection. In clinical practice this means that in case of a longer time-to-isolation than the given numbers, peri-procedural adenosine testing (ERC test) or additional freezing is advised.