Fehmi Keçe

Chapter 2 32 Table 1a. Overview of literature on radiofrequency ablation. Author, year (study type) Number of patients and type of ablation device PAF (%) Preventive techniques AAD free survival (1 year) (%) Procedural and ablation time (min) Complications (%) Aryana, 2015 (82) (retrospective) N=423 RF 76 Power reduction (40W anterior, 30W posterior) 60 (P<0.001) 188 (p<0.001) 66 (p<0.001) - Pericardial effusion/ Cardiac tamponade 1.7 - Transient ST elevation 0.2 - Vascular access 0.2 - Venous thromboembolism 0.2 - Other: pacemaker insertion 0.2 Chun, 2017 (122)(registry) N=1559 RF N=556 RFA 43 Power reduction (40W anterior and 30 W posterior and inferior) N.A. 101 (p=0.004) N.A. - Cardiac tamponade 0.5 (p=0.024) - Stroke/TIA 0.2 - Atrial-oesophageal fistula 0.05 - Vascular access 2.6 - Other: Hemothorax 0.1 Khoueiry, 2016 (86) (observational) N=376 RFA 100 Power reduction (30W anterior, 25W posterior). Temperature limitation 48°C 86 114 N.A - Pericarditis/Cardiac tamponade 1.6 - Thromboembolic events 0.3 - Transient phrenic palsy 0.3 (p=0.016) - Upper digestive bleeding 0.3 - Vascular access /major bleeding 3.2 - Other 1.0 (haematuria, haemoptysis, and anaphylactic shock) Kuck, 2016 (87) (multicenter RCT) N=284 RF N= 93 RFA 100 Power reduction (40W anterior and inferior, 30W posterior) 64 124 (p<0.001) N.A. - Pericardial effusion/Cardiac tamponade 1.3 - Transient neurologic complication 0.8 and Stroke/TIA 0.5 - Gastrointestinal complications 0.5 - Vascular access 4.3 - Other 2.7 (pulmonary or bronchial complication 1.1, dyspnea 0.5, contrast media reaction 0.3, contusion 0.3, hematuria 0.3 and local oedema 0.3)