Fehmi Keçe

Chapter 3 96 Table C. Coagulation activity. Ablation Technology T1 T2 T3 T4 P -value (group) P-value (time) P -value (interaction) Intrinsic (APTT) and extrinsic (PT) coagulation APTT (s) PVAC Gold 37 ± 4 120 ± 0 120 ± 3 38 ± 5 0.830 0.001 0.607 TC 37 ± 3 120 ± 0 120 ± 0 38 ± 3 PT (s) PVAC Gold 37 ± 7 43 ± 10 37 ± 8 35 ± 7 0.307 0.001 0.009 TC 36 ± 9 39 ± 7 37 ± 7 35 ± 7 INR PVAC Gold 2.4 ± 0.5 2.8 ± 0.6 2.5 ± 0.5 2.3 ± 0.4 0.359 0.001 0.021 TC 2.6 ± 0.4 2.6 ± 0.4 2.5 ± 0.4 2.3 ± 0.4 Fibrin turnover (Marker of activated fibrinolysis) DD (µg/L) PVAC Gold 291 ± 145 266 ± 114 285 ± 115 329 ± 150 0.778 0.001 0.042 TC 259 ± 53 278 ± 66 279 ± 75 328 ± 139 Coagulant potential (Acute phase coagulation marker) Fib (g/L) PVAC Gold 3.4 ± 0.6 2.9 ± 0.6 3.0 ± 0.6 3.5 ± 0.7 0.306 0.001 0.002 TC 3.6 ± 0.6 3.2 ± 0.5 3.1 ± 0.6 3.7 ± 0.6 Endothelial damage (Main alterations of coagulation) VWF (kIU/mL) PVAC Gold 1.3 ± 0.3 1.1 ± 0.3 1.3 ± 0.5 1.7 ± 0.5 0.191 0.001 0.243 TC 1.5 ± 0.6 1.3 ± 0.6 1.4 ± 0.7 1.8 ± 0.7 Thrombin generation (Markers of activated coagulation) F1+2 (ng/L) PVAC Gold 1239 ± 595 1256 ± 608 1086 ± 539 1279 ± 692 0.183 0.001 0.567 TC 1089 ± 392 1178 ± 397 902 ± 313 1117 ± 560