Ellen de Kort

26 Chapter 2 Table 1. Characteristics of included studies Author Kind of study Inclusion criteria INSURE Exclusion criteria INSURE Ancora et al. 26 Retrospective case control study FiO 2 requirement >0.40 on nCPAP >30 min to maintain SpO 2 values 85-95% in presence of radiological signs of RDS Not reported Van den Berg et al. 22 Prospective cohort study Not reported Not reported Bohlin et al. 23 Retrospective descriptive study Preterm with RDS on nCPAP with a/A ratio ≤0.22 Infants requiring intubation as part of resuscitation at birth Cherif et al. 20 Retrospective case study GA >27 weeks, a/A ratio ≤0.25 on nCPAP Not reported Gizzi et al. 25 Retrospective case study FiO 2 requirement >0.40 on nCPAP >30 min to maintain SpO 2 values 85-93% in the presence of radiologic signs of RDS Not reported Flor-de-Lima et al. 18 Retrospective case control study FiO 2 >0.40 with respiratory distress and/or arterial pCO 2 >65 mmHg and pH <7.0 on nCPAP Not reported Leone et al. 27 Case control study Preterm with RDS on nCPAP with a/A ratio ≤0.22 Infants requiring intubation as part of resuscitation at birth or later as part of respiratory failure Sandri et al. 24 RCT GA 28-32 weeks, inborn, FiO 2 on nCPAP >0.40 for >30 min to maintain SpO 2 93-96% and radiographic signs of RDS