Ellen de Kort

58 Chapter 4 compared to LISA procedures in which the first attempt failed. However, in procedures in which the first attempt was successful, the performer of the procedure was significantly more often a neonatologist than in procedures in which the first attempt failed (73% versus 33%, p <0.001). Table 2a. Patient characteristics and performer experience in relation to success rate Success n = 45 Failure n = 41 p-value Patient characteristics Gestational age (week), median (IQR) 28.3 (26.7-29.4) 28.4 (25.9-29.9) 0.92 Birth weight (g), median (IQR) 1,030 (763-1,300) 1,000 (750-1,328) 0.94 Birth weight < 10 th percentile, n (%) 13 (29) 12 (29) 1.00 Postnatal age (h), median (IQR) 3.3 (2.1-11.6) 3.3 (2.1-7.3) 0.58 Male gender, n (%) 25 (56) 24 (59) 0.83 Procedure characteristics First attempt by neonatologist, n (%) 33 (73) 13 (33) a <0.001 Good technical quality, n (%) 34 (76) 11 (35) b 0.001 a For one procedure the performer was not reported; b For ten procedures quality of technical conditions was missing. Technical quality assessment Information about the quality of technical conditions was available for 76 LISA procedures (88%). Quality was good in 45 procedures (59%) and inadequate in 31 procedures (41%). Table 2b shows the patient characteristics and experience of the performer in procedures with good andwith inadequate quality assessment. There were no statistically significant differences in patient characteristics or in the level of experience of the performer between procedures with good and with inadequate technical quality. Quality assessment was, however, related to the success of the first attempt. Of the 45 procedures in which the first attempt was successful, technical qualitywas good in 34 procedures (76%), whereas of the 31 procedures in which the first attempt failed, only 11 procedures (35%) had good technical quality (p = 0.001). Vital parameters Figure 2 shows heart rate and oxygen saturation at baseline and at different time points after start of the LISA procedure. Heart rate significantly increased compared to baseline at all time points with the exception of t = 1 min. Oxygen saturation did not change significantly from baseline at all time points with the exception of t = 1 and t = 2 min, in which oxygen saturation was significantly lower compared to baseline.