Cindy Boer

Cindy Germaine Boer The works described in this thesis was conducted at the department of Internal Medicine at the Erasmus MC University Medical Center Rotterdam, the Netherlands. The Rotterdam study is funded by Erasmus MC University Medical Center and Erasmus University Rotterdam; the Netherlands Organization for Scientific Research (NWO); the Netherlands Organization for Health Research and Development (ZonMW); the Research institute for Diseases in the elderly (RIDE); the Dutch Ministry of Education, Culture and Science; the Dutch Ministry of Health, Welfare and sports; the European Commission (DG XII); and the municipality of Rotterdam. ISBN: 978-94-6416-105-2 Cover Design: Cindy G. Boer Design: Cindy G. Boer and Ridderprint Illustrations: Cindy G. Boer Layout and printing: Ridderprint © Cindy Germaine Boer | 2020 All rights reserved. No part of this book may be reproduced, stored in a retrieval system or transmitted in any form or by any means, without prior written permission of the author, or, the scientific journal in which parts of the book have been published.