Cindy Boer

General Discussion | 275 6 46. Albert, H.B., et al., Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy. Eur Spine J, 2013. 22(4): p. 697-707. 47. Bråten, L.C.H., et al., Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial. Bmj, 2019. 367: p. l5654. 48. Jansen, P.R., et al., Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Nat Genet, 2019. 51(3): p. 394-403. 49. Lee, J.J., et al., Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nat Genet, 2018. 50(8): p. 1112-1121. 50. Peterson, R.E., et al., Genome-wide Association Studies in Ancestrally Diverse Populations: Oppor- tunities, Methods, Pitfalls, and Recommendations. Cell, 2019. 179(3): p. 589-603. 51. Bien, S.A., et al., The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE. Annu Rev Genomics Hum Genet, 2019. 20: p. 181-200. 52. Tozzi, V., et al., Global, pathway and gene coverage of three Illumina arrays with respect to inflam- matory and immune-related pathways. Eur J Hum Genet, 2019. 27(11): p. 1716-1723. 53. Brody, J.A., et al., Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology. Nat Genet, 2017. 49(11): p. 1560-1563. 54. Deveza, L.A. and R.F. Loeser, Is osteoarthritis one disease or a collection of many? Rheumatology (Oxford), 2018. 57(suppl_4): p. iv34-iv42. 55. Thaiss, C.A. and E. Elinav, The remedy within: will the microbiome fulfill its therapeutic promise? J Mol Med (Berl), 2017. 95(10): p. 1021-1027. 56. Descamps, H.C., et al., The path toward using microbial metabolites as therapies. EBioMedicine, 2019. 44: p. 747-754. 57. Cherian, J.J., et al., Preliminary results of a phase II randomized study to determine the efficacy and safety of genetically engineered allogeneic human chondrocytes expressing TGF-β1 in patients with grade 3 chronic degenerative joint disease of the knee. Osteoarthritis Cartilage, 2015. 23(12): p. 2109-2118. 58. Pan, W., et al., Inhibition of Ctsk alleviates periodontitis and comorbid rheumatoid arthritis via downregulation of the TLR9 signalling pathwa