Cindy Boer

Cartilage Thickness and Hip Osteoarthritis | 91 2.1 2014;43: D174–D180. doi: 10.1093/nar/gku1060 35. Tsuchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, et al. GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes. J Biol Chem. 2010;285: 8395–407. doi: 10.1074/jbc. M109.038638 36. Evangelou E, Valdes a M, Kerkhof HJM, Styrkarsdottir U, Zhu YY, Meulenbelt I, et al. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chro- mosome 7q22. Ann Rheum Dis. 2013;70: 349–355. doi: 10.1136/ard.2010.132787.Meta-analysis 37. Reynard LN. Analysis of genetics and DNA methylation in osteoarthritis: What have we learnt about the disease? Semin Cell Dev Biol. 2016; doi: 10.1016/j.semcdb.2016.04.017 38. van Meurs JBJ, Uitterlinden a G. Osteoarthritis year 2012 in review: genetics and genomics. Osteo- arthritis Cartilage. Elsevier Ltd; 2012;20: 1470–6. doi: 10.1016/j.joca.2012.08.007 39. Willer CJ, Li Y, Abecasis GR. METAL: Fast and efficient meta-analysis of genomewide association scans. Bioinformatics. 2010;26: 2190–2191. doi: 10.1093/bioinformatics/btq340 40. Yang J, Lee SH, Goddard ME, Visscher PM. GCTA: A tool for genome-wide complex trait analy- sis. Am J Hum Genet. The American Society of Human Genetics; 2011;88: 76–82. doi: 10.1016/j. ajhg.2010.11.011 41. Reijman M, Hazes JMW, Pols HAP, Bernsen RMD, Koes BW, Bierma-Zeinstra SMA. Validity and re- liability of three definitions of hip osteoarthritis: cross sectional and longitudinal approach. Ann Rheum Dis. 2004;63: 1427–33. doi: 10.1136/ard.2003.016477 [PMC free article] [PubMed] 42. Lane NE, Nevitt MC, Hochberg MC, Hung Y-Y, Palermo L. Progression of radiographic hip osteoar- thritis over eight years in a community sample of elderly white women. Arthritis Rheum. 2004;50: 1477–86. doi: 10.1002/art.20213 43. Kinds MB, Vincken KL, Vignon EP, ten Wolde S, Bijlsma JWJ, Welsing PMJ, et al. Radiographic fea- tures of knee and hip osteoarthritis represent characteristics of an individual, in addition to sever- ity of osteoarthritis. Scand J Rheumatol. 2012;41: 141–9. doi: 10.3109/03009742.2011.617311 44. Nevitt MC, Lane NE, Scott JC, Hochberg MC, Pressman a. R, Genant HK, et al. Radiographic osteo- arthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group. Arthritis Rheum. 1995;38: 907–16. 45. Valdes AM, McWilliams D, Arden NK, Doherty SA, Wheeler M, Muir KR, et al. Involvement of dif- ferent risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. Arthritis Rheum. 2010;62: 2688–95. doi: 10.1002/art.27574 46. Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler a. M, et al. The Human Genome Browser at UCSC. Genome Res. 2002;12: 996–1006. doi: 10.1101/gr.229102 47. Ward LD, Kellis M. HaploReg: A resource for exploring chromatin states, conservation, and regula- tory motif alterations within sets of genetically linked variants. Nucleic Acids Res. 2012;40: 930– 934. doi: 10.1093/nar/gkr917 48. Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O’Donnell CJ, De Bakker PIW. SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics. 2008;24: 2938– 2939. doi: 10.1093/bioinformatics/btn564