Anne-Marie Koop

3 101 SUPPLEMENTARY MATERIAL Search strategy 1. Component ‘right ventricle’ “right ventricle”[tiab] OR “right ventricles”[tiab] OR “right ventricular”[tiab] OR “ventriculus dexter”[tiab] OR “right heart”[tiab] OR “RV”[tiab] 2. Component ‘pressure load’ “pressure load”[tiab] OR “ pressure loading”[tiab] OR “ pressure loaded”[tiab] OR “ pressure loads”[tiab] OR “ pressure overload”[tiab] OR “ pressure overloading”[tiab] OR “ pressure overloaded”[tiab] OR “pressure overloads”[tiab] OR “increased afterload”[tiab] OR “increased afterloading”[tiab] OR “afterloaded”[tiab] OR “increased afterloads”[tiab] OR “pulmonary artery banding”[tiab] OR “ pulmonary hypertension”[tiab] OR “pulmonary arterial hypertension”[tiab] OR “pulmonary valve stenosis”[tiab] OR “pulmonary valve calcification”[tiab] OR “calcification pulmonary valve”[tiab] OR “pulmonary valve diseases”[tiab] OR “pulmonary valve disease”[tiab] OR “pulmonary stenosis”[tiab] OR “stenosis pulmonary valve”[tiab] OR “pulmonary outflow tract obstruction”[tiab] OR “obstruction pulmonary outflow tract”[tiab] OR “pulmonary artery obstruction”[tiab] OR “pulmonary artery stenosis”[tiab] 3. Component ‘metabolism’ “metabolism”[tiab] OR “metabolic”[tiab] OR “energy metabolism”[tiab] OR “basal metabolism”[tiab] OR “carbohydrate metabolism”[tiab] OR “metabolic network”[tiab] OR “metabolic pathways”[tiab] OR “metabolic networks and pathways”[tiab] OR “biosynthetic pathways”[tiab] OR “metabolic activation”[tiab] OR “metabolic inactivation”[tiab] OR “secondary metabolism”[tiab] OR “metabolic remodeling”[tiab] OR “metabolic remodelling”[tiab] OR “metabolic”[tiab] OR “metabolic reprogramming”[tiab] OR “metabolite”[tiab] OR “metabolomic”[tiab] OR “metabolomics”[tiab] OR “metabolite profile”[tiab] OR “metabolites profiles”[tiab] OR “metabolite derangements”[tiab] OR “metabolomic signatures”[tiab] OR “substrate flux”[tiab] OR “mitochondria”[tiab] OR “mitochondrial”[tiab]OR“mitochondrion”[tiab]OR“mitochondrialenergytransduction”[tiab] OR “glucose metabolism”[tiab] OR “ glucose oxidation”[tiab] OR “gluconeogenesis”[tiab] OR “glycogenolysis”[tiab] OR “glycolysis”[tiab] OR “glycosylation”[tiab] OR “pyruvate”[tiab] OR “glucose”[tiab] OR “pentose phosphate pathway”[tiab] OR “fatty acid”[tiab] OR “fatty acids”[tiab] OR “long chain fatty acids”[tiab] OR “lipid metabolism”[tiab] OR “lipolysis”[tiab] OR “lipoylation”[tiab] OR “fatty acid oxidation”[tiab] OR “lipotoxicity”[tiab] OR “triglyceride”[tiab] OR “ceramide”[tiab] OR “lipid deposition”[tiab] OR “beta-oxidation”[tiab] OR “beta oxidation”[tiab] OR “fatty acid transport”[tiab] OR “β -oxidation”[tiab] OR “branched chain amino acids”[tiab] OR “branched chain amino acid”[tiab] OR “amino acid”[tiab]