Anne-Marie Koop

128 Supplemental table 2.Meta-regression analyses: variables versus duration of RV pressure load. coefficient constant std.error t P > |t| [95% conf. interval] FDG-uptake -0.006 1.831118 0.028237 -0.21 0.851 -0.12751 0.115473 GLUT1 mRNA 0 .007318 1.338181 0 .017441 0.42 0.681 -0.03009 0.044725 GLUT1 protein -0.06177 5.544784 0.193256 -0.32 0.780 -0.89329 0.769742 GLUT4 mRNA -0.08868 -0.1779 0.094733 -0.94 0.385 -0.32048 0.143124 GLUT4 protein 0.062796 -1.92728 0.044244 1.42 0.251 -0.07801 0.2036 HK1 mRNA -0.41346 20.52151 0.203145 -2.04 0.081 -0.89382 0.066904 HK2 mRNA 0.013838 -0.26506 0.035005 0.4 0.703 -0.06688 0.09456 CTP1B mRNA -0.26705 9.571756 0.071064 -3.76 0.033 -0.49321 -0.0409 mitochondrial content -0.0066 -0.41463 0 .009553 -0.69 0.507 -0. 02821 0.015005 mitochondrial content (first 6 weeks only) -0.12221 2.461455 0.025414 -4.81 0.002 -0.1823 -0.06211 PDH mRNA -0.0066 -0.26024 0.071658 -0.09 0.935 -0.31492 0.301721 PDK4 mRNA -0.20665 0 .005799 0.178042 -1.16 0.310 -0.70097 0.287676 PGC1a mRNA -0.06271 0.634076 0.021666 -2.89 0.044 -0.12287 -0.00256 PGC1a protein -0.04477 0.977281 0.03338 -1.34 0.272 -0.151 0.061461 PPAR mRNA -0.03096 0.785598 0.023265 -1.33 0.232 -.0878866 0.025968 MCAD mRNA -0.10478 -3.09365 0.096481 -1.09 0.313 -0.33292 0.123366 MCAD protein 0.120205 -5.58791 0.080062 1.5 0.272 -0.22427 0.464684 resp. cap. Glucose - ADP driven -0.00781 -0.53042 0 .009609 -0.81 0.566 -0. 1299 0.114282 resp. cap. Glucose - whole cells -0.11876 3.300385 0.114537 -1.04 0.409 -0.61157 0.374057 resp. cap. FA - ADP driven -0 .00753 -0.49098 0. 010332 -0.73 0.519 -0.04041 0.025351 Significant p-values shown in bold .