Anne-Marie Koop

130 Supplemental table 4. Level of significance of meta-analysis and meta-regression. mRNA expression level protein expression level parameter meta- analysis model effect (increased compared) duration effect effect of degree of pressure load meta- analysis model effect (increased compared) duration effect effect of degree of pressure load GLUT1 ↑ (0.000) ~ ~ ~ ↑ (0.009) MCT vs. hypoxia, PAB and FHR ~ ~ GLUT4 ~ ~ ~ ~ ~ ~ ~ ~ CTP1B ~ ~ ↓ (0.033) N/A N/A N/A N/A N/A HK1 ↑ (0.000) ~ ↘ (0.081) ~ N/A N/A N/A N/A HK2 ~ ~ ~ ~ N/A N/A N/A N/A PDH ~ ~ ~ ~ ↘ (0.123) ~ ~ N/A PDK4 ↘ (0.110) ~ ~ ~ ~ ~ N/A - PDK1 N/A N/A N/A ~ ~ ~ N/A ~ PDK2 N/A N/A N/A N/A ~ ~ N/A N/A MCAD ↓ (0.000) ~ ~ ~ ↘ (0.141) ~ ~ ~ PGC1α ↓ (0.008) ~ ↓ (0.044) ~ ~ MCT vs. SuHx ~ N/A PPARα ~ ~ ~ N/A N/A N/A N/A N/A