Anne-Marie Koop

212 Figure 4. Representative results of morphological and functional changes. The first panel shows RV parameters: RV EDV (A), RV ESV (B), RV EF (C), RV ED mass (E), and RV ES mass (F). The LV parameters are shown in the second panel: LV EDV (G), LV ESV (H), LV EF (I), LV SV (J), LV ED mass (K), and LV ES mass (L). Septal deviation is represented by the eccentricity index ED (M) and ES (N). Cardiac dimensions are shown in representative images (O). Heart rate (P) and cardiac output (Q) are also shown. The changes were observed due to 6 weeks of PAB measured by CMR in the sham (n = 5) and pulmonary artery banding (PAB, n = 8) groups. The statistical analyses were performed using the Mann-Whitney test. Values are presented as median and interquartile range. * = p < 0.05 compared to sham. β = individual animal. RV = right ventricle. LV = left ventricle. ED = end diastolic. ES = end systolic. EDV = ED volume. ESV = ES volume. SV = stroke volume. CO = cardiac output. EF = ejection fraction.