Anne-Marie Koop

9 317 27. Drozd K, Ahmadi A, Deng Y, Jiang B, Petryk J, Thorn S, Stewart D, Beanlands R, DeKemp RA, DaSilva JN, Mielniczuk LM. Effects of an endothelin receptor antagonist, Macitentan, on right ventricular substrate utilization and function in a Sugen 5416/hypoxia rat model of severe pulmonary arterial hypertension. J Nucl Cardiol L.M. Mielniczuk, Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada; 2016;1–11. 28. Bruggen CE van der, Happé CM, Dorfmüller P, Trip P, Spruijt OA, Rol N, Hoevenaars FP, Houweling AC, Girerd B, Marcus JT, Mercier O, Humbert M, Handoko ML, Velden J van der, Vonk Noordegraaf A, Bogaard HJ, Goumans M-J, Man FS de. Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial HypertensionCLINICAL PERSPECTIVE. Circulation 2016;133:1747–1760. 29. Adrogue J V, Sharma S, Ngumbela K, Essop MF, Taegtmeyer H. Acclimatization to chronic hypobaric hypoxia is associated with a differential transcriptional profile between the right and left ventricle. Mol Cell Biochem H. Taegtmeyer, Department of Internal Medicine, Division of Cardiology, University of Texas Houston - Medical School, Houston, TX 77030, United States; 2005;278:71–78. 30. Sivitz WI, Lund DD, Yorek B, Grover-McKay M, Schmid PG. Pretranslational regulation of two cardiac glucose transporters in rats exposed to hypobaric hypoxia. Am J Physiol - Endocrinol Metab W.I. Sivitz, Dept. of Internal Medicine, Univ. of Iowa Hospitals and Clinics, Iowa City, IA 52246, United States; 1992;263:E562–E569. 31. Sharma S, Taegtmeyer H, Adrogue J, Razeghi P, Sen S, Ngumbela K, Essop MF. Dynamic changes of gene expression in hypoxia-induced right ventricular hypertrophy. Am J Physiol - Hear Circ Physiol H. Taegtmeyer, Dept. of Internal Medicine, Division of Cardiology, Univ. of Texas-Houston Med. School, Houston, TX 77030, United States; 2004;286:H1185–H1192. 32. Gomez-Arroyo J, Mizuno S, Szczepanek K, Tassell B Van, Natarajan R, Remedios CG Dos, Drake JI, Farkas L, Kraskauskas D, Wijesinghe DS, Chalfant CE, Bigbee J, Abbate A, Lesnefsky EJ, Bogaard HJ, Voelkel NF. Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension. Circ Hear Fail N.F. Voelkel, Victoria Johnson Center for Lung Obstructive Disease Research, Virginia Commonwealth University, Richmond, VA 23298, United States; 2013;6:136–144. 33. Piao L, Fang YH, Cadete VJJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: Resuscitating the hibernating right ventricle. J Mol Med 2010;88:47–60. 34. Piao L, Fang Y-H, Parikh K, Ryan JJ, Toth PT, Archer SL. Cardiac glutaminolysis: A maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. J Mol Med S.L. Archer, Department of Medicine, Queen’s University, Etherington Hall, Kingston, ON K7L 3N6, Canada; 2013;91:1185–1197. 35. Balestra GM, Mik EG, Eerbeek O, Specht PAC, Laarse WJ van der, Zuurbier CJ. Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: Mitochondrial inhibition as driver of cardiac failure? Respir Res C.J. Zuurbier, Department of Anesthesiology, Laboratory of Experimental Intensive Care and Anesthesiology, AMC, Amsterdam, Netherlands; 2015;16.

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