Sara van den Berg

127 5 Hallmarks of CMV-specific T-cells 17. Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, et al. Memory CD8+ T-cells vary in differentiation phenotype in different persistent virus infections. Nat Med. 2002;8(4):379-85. 18. van Baarle D, Kostense S, van Oers MH, Hamann D, Miedema F. Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue. Trends Immunol. 2002;23(12):586- 91. 19. Wills MR, Okecha G, Weekes MP, Gandhi MK, Sissons PJ, Carmichael AJ. Identification of naive or antigen-experienced human CD8(+) T-cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8(+) T-cell response. J Immunol. 2002;168(11):5455-64. 20. van Leeuwen EM, Koning JJ, Remmerswaal EB, van BD, van Lier RA, ten Berge IJ. Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T-cells. J Immunol. 2006;177(8):4998-5005. 21. Pipeling MR, West EE, Osborne CM, Whitlock AB, Dropulic LK, Willett MH, et al. Differential CMV- specific CD8+ effector T-cell responses in the lung allograft predominate over the blood during human primary infection. J Immunol. 2008;181(1):546-56. 22. Welten SP, Redeker A, Franken KL, Benedict CA, Yagita H, Wensveen FM, et al. CD27-CD70 costimulation controls T-cell immunity during acute and persistent cytomegalovirus infection. J Virol. 2013;87(12):6851-65. 23. Arens R, Loewendorf A, Her MJ, Schneider-Ohrum K, Shellam GR, Janssen E, et al. B7-mediated costimulation of CD4 T-cells constrains cytomegalovirus persistence. J Virol. 2011;85(1):390-6. 24. Arens R, Loewendorf A, Redeker A, Sierro S, Boon L, Klenerman P, et al. Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T-cell populations. J Immunol. 2011;186(7):3874-81. 25. Welten SP, Melief CJ, Arens R. The distinct role of T-cell costimulation in antiviral immunity. Curr Opin Virol. 2013;3(4):475-82. 26. Welten SP, Redeker A, Franken KL, Oduro JD, Ossendorp F, Cicin-Sain L, et al. The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T-cell expansion. Elife. 2015;4:e07486. 27. Humphreys IR, Loewendorf A, De TC, Schneider K, Benedict CA, Munks MW, et al. OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T-cells: A CD4-dependent mechanism. J Immunol. 2007;179(4):2195-202. 28. Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, et al. Coregulation of CD8+ T-cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol. 2009;10(1):29-37. 29. Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, et al. Restoring function in exhausted CD8 T-cells during chronic viral infection. Nature. 2006;439(7077):682-7. 30. Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T-cells leads to reversible immune dysfunction. Nat Med. 2006;12(10):1198-202. 31. Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, et al. PD-1 expression on HIV-specific T-cells is associated with T-cell exhaustion and disease progression. Nature. 2006;443(7109):350-4. 32. He XH, Jia QT, Li FY, Saltis M, Liu Y, Xu LH, et al. CD8(+) T-cells specific for both persistent and non-persistent viruses display distinct differentiation phenotypes but have similar level of PD-1 expression in healthy Chinese individuals. Clin Immunol. 2008;126(2):222-34.

RkJQdWJsaXNoZXIy ODAyMDc0