Sara van den Berg

168 Chapter 6 Supplementary Figure 6. Fits of mathematical model to the deuterium enrichment data of CD8 + T-cells. Best fits of the kinetic heterogeneity model to the enrichment in true naïve (T TN ), central memory (T CM ), effector memory (T EM/EMRA ), and CMV-specific CD8 + T-cells. Label enrichment in the DNA was scaled between 0 and 100% by normalizing for the maximum enrichment in granulocytes (see Materials and methods ). The measurements that were out of range of the standards are indicated in red open symbols, those in range are indicated in black closed symbols.