Sara van den Berg

218 Chapter 8 REFERENCES 1. Olsson, J., et al., Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study. Mech Ageing Dev, 2000. 121(1-3): p. 187-201. 2. Wikby, A., et al., Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Exp Gerontol, 2002. 37(2-3): p. 445-53. 3. Redeker, A., et al., The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose. Front Immunol, 2017. 8: p. 1953. 4. Mekker, A., et al., Immune senescence: relative contributions of age and cytomegalovirus infection. PLoS Pathog, 2012. 8(8): p. e1002850. 5. Komatsu, H., et al., Population analysis of antiviral T-cell responses using MHC class I-peptide tetramers. Clin Exp Immunol, 2003. 134(1): p. 9-12. 6. Karrer, U., et al., Memory inflation: continuous accumulation of antiviral CD8+ T-cells over time. J Immunol, 2003. 170(4): p. 2022-9. 7. Klenerman, P., The (gradual) rise of memory inflation. Immunol Rev, 2018. 283(1): p. 99-112. 8. Trzonkowski, P., et al., Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence. Vaccine, 2003. 21(25-26): p. 3826-36. 9. Wald, A., et al., Impact of human cytomegalovirus (CMV) infection on immune response to pandemic 2009 H1N1 influenza vaccine in healthy adults. J Med Virol, 2013. 85(9): p. 1557-60. 10. Savva, G.M., et al., Cytomegalovirus infection is associated with increased mortality in the older population. Aging Cell, 2013. 12(3): p. 381-7. 11. Gkrania-Klotsas, E., et al., Seropositivity and Higher Immunoglobulin G Antibody Levels Against Cytomegalovirus Are Associated With Mortality in the Population-Based European Prospective Investigation of Cancer–Norfolk Cohort. Clinical Infectious Diseases, 2013. 56(10): p. 1421-1427. 12. Roberts, E.T., et al., Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-up. Am J Epidemiol, 2010. 172(4): p. 363-71. 13. Wang, G.C., et al., Cytomegalovirus infection and the risk of mortality and frailty in older women: a prospective observational cohort study. Am J Epidemiol, 2010. 171(10): p. 1144-52. 14. Cicin-Sain, L., et al., Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging. PLoS Pathog, 2012. 8(8): p. e1002849. 15. Furman, D., et al., Cytomegalovirus infection enhances the immune response to influenza. Science Translational Medicine, 2015. 7(281). 16. Trzonkowski, P., et al., From bench to bedside and back: The SENIEUR Protocol and the efficacy of influenza vaccination in the elderly. Biogerontology, 2009. 10(1): p. 83-94. 17. Wald, A., et al., Impact of human cytomegalovirus (CMV) infection on immune response to pandemic 2009 H1N1 influenza vaccine in healthy adults. Journal of Medical Virology, 2013. 85(9): p. 1557-1560. 18. Strindhall, J., et al., Humoral response to influenza vaccination in relation to pre-vaccination antibody titres, vaccination history, cytomegalovirus serostatus and CD4/CD8 ratio. Infectious Diseases, 2016. 48(6): p. 436-442. 19. Merani, S., et al., Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection. Front Immunol, 2017. 8: p. 784.