Sara van den Berg

44 Chapter 2 Influenza antibody titer Protection Parameter B (beta) Standard Error Sig (P-value) B (beta) Standard Error Sig (P-value) (Intercept) 3.844 0.3311 0 -0.794 0.419 0.058 Age group 2 (40-52 year) -0.485 0.3022 0.109 -0.527 0.432 0.222 Age group 1 (30-40 year) 0.438 0.3215 0.173 0.606 0.443 0.171 Age group 0 (18-30 year) 0 a . . 0 a . . Sex male -0.226 0.2302 0.326 -0.495 0.333 0.137 Sex female 0 a . . 0 a . . Previous influenza vaccinations yes -0.394 0.3869 0.309 -0.689 0.571 0.228 Previous influenza vaccinations sometimes -0.392 0.2664 0.142 -0.251 0.417 0.548 Previous influenza vaccinations no 0 a . . 0 a . . Seasonal 2009 vaccination before study yes -0.37 0.2902 0.203 0.110 0.459 0.810 Seasonal 2009 vaccination before study no 0 a . . 0 a . . Seasonal 2009 vaccination during study yes -0.055 0.2745 0.841 -0.454 0.402 0.258 Seasonal 2009 vaccination during study no 0 a . . 0 a . . CMV IgG group high -0.208 0.335 0.535 -0.387 0.533 0.468 CMV IgG group medium -0.019 0.3543 0.957 0 a . . CMV IgG group low 0 a . . 0 a . . Timepoint 5 2.83 0.3081 < 0.001 2.922 0.527 < 0.001 Timepoint 4 3.357 0.2884 < 0.001 3.643 0.573 < 0.001 Timepoint 3 4.404 0.326 < 0.001 4.075 0.605 < 0.001 Timepoint 2 4.012 0.3443 < 0.001 3.314 0.511 < 0.001 Timepoint 1 0 a . . 0 a . . CMV IgG group high * Timepoint 5 0.459 0.4242 0.279 1.147 0.767 0.135 CMV IgG group high * Timepoint 4 0.278 0.3884 0.475 0.390 0.734 0.596 CMV IgG group high * Timepoint 3 0.293 0.4027 0.467 2.238 1.278 0.080 CMV IgG group high * Timepoint 2 0.388 0.4392 0.377 1.275 0.738 0.084 CMV IgG group high * Timepoint 1 0 a . . 0 a . . CMV IgG group medium * Timepoint 5 -0.226 0.4282 0.597 -0.364 0.723 0.614 CMV IgG group medium * Timepoint 4 -0.048 0.3668 0.895 0.219 0.752 0.771 CMV IgG group medium * Timepoint 3 -0.084 0.4223 0.843 0.362 0.866 0.676 CMV IgG group medium * Timepoint 2 0.195 0.4474 0.663 0.330 0.703 0.638 CMV IgG group medium * Timepoint 1 0 a . . 0 a CMV IgG group low * Timepoint 5 0 a . . 0 a CMV IgG group low * Timepoint 4 0 a . . 0 a CMV IgG group low * Timepoint 3 0 a . . 0 a CMV IgG group low * Timepoint 2 0 a . . 0 a . . CMV IgG group low * Timepoint 1 0 a . . 0 a . . Supplementary Table 3. Regression table effect CMV IgG group on pandemic influenza vaccine response of H1N1pdm strain in the pandemic season. Bold: p value < 0.10 Bold and underlined: p value < 0.05. a reference category