Sara van den Berg

46 Chapter 2 Influenza antibody titer Protection Parameter B (beta) Standard Error Sig (P-value) B (beta) Standard Error Sig (P-value) (Intercept) 7.321 0.3907 0 3.920744 1.127556 0.001 Age group 2 (40-52 year) -0.969 0.4197 0.021 -1.06577 0.777988 0.171 Age group 1 (30-40 year) -0.663 0.4203 0.115 # Age group 0 (18-30 year) 0 a . . 0 a . . Sex male -0.599 0.2927 0.041 -1.35677 0.665921 0.042 Sex female 0 a . . 0 a . . Previous influenza vaccinations yes -0.55 0.4719 0.244 0.066665 0.996880 0.947 Previous influenza vaccinations sometimes -0.489 0.4355 0.261 -0.52934 0.897337 0.555 Previous influenza vaccinations no 0 a . . 0 a . . Seasonal 2009 vaccination yes -0.418 0.3913 0.286 -1.34266 1.088206 0.217 Seasonal 2009 vaccination no 0 a . . 0 a . . CMV IgG group high 1.295 0.4562 0.005 1.76129 0.897221 0.05 CMV IgG group medium -0.149 0.5024 0.767 -0.61748 0.765129 0.42 CMV IgG group low 0 a . . 0 a . . Timepoint 3 0.986 0.2243 0 0.495826 0.364392 0.174 Timepoint 2 1.887 0.2159 0 1.62821 0.810095 0.044 Timepoint 1 0 a . . 0 a . . CMV IgG group high * Timepoint 3 -0.209 0.3584 0.56 0.258459 1.355159 0.849 CMV IgG group high * Timepoint 2 -0.615 0.3293 0.062 -0.87393 1.531723 0.568 CMV IgG group high * Timepoint 1 0 a . . 0 a . . CMV IgG group medium * Timepoint 3 -0.191 0.3379 0.573 0.262801 0.586560 0.654 CMV IgG group medium * Timepoint 2 -0.064 0.417 0.878 0.50072 1.231240 0.684 CMV IgG group medium * Timepoint 1 0 a . . 0 a CMV IgG group low * Timepoint 3 0 a . . 0 a CMV IgG group low * Timepoint 2 0 a . . 0 a CMV IgG group low * Timepoint 1 0 a . . 0 a Supplementary Table 5. Regression table effect CMV IgG group serostatus on seasonal influenza vaccine response of H1N1pdm strain in the season 2010-2011. Bold: p value <0.10 Bold and underlined: p value <0.05. # for age group 0 (18-30 year) all participants were protected after vaccination (outcome 1) wherefore the model did not run. This is solved merging age group 0 and 1 for this model, resulting in no separate regression coefficient for age group 1. a reference category