Sara van den Berg

47 2 CMV on influenza vaccination Influenza antibody titer Protection Parameter B (beta) Standard Error Sig (P-value) B (beta) Standard Error Sig (P-value) (Intercept) 3.937 0.4387 0 -1.055 0.571 0.065 Age group 2 (40-52 year) 0.044 0.4029 0.913 -0.351 0.5248 0.504 Age group 1 (30-40 year) -0.239 0.4554 0.6 -0.516 0.5764 0.371 Age group 0 (18-30 year) 0 a . . 0 a . . Sex male -0.023 0.2778 0.933 0.215 0.3255 0.508 Sex female 0 a . . 0 a . . Previous influenza vaccinations yes -0.224 0.4314 0.604 -0.069 0.4824 0.886 Previous influenza vaccinations sometimes -0.06 0.3824 0.875 0.422 0.4741 0.373 Previous influenza vaccinations no 0 a . . 0 a . . Seasonal 2009 vaccination yes 0.729 0.4627 0.115 0.868 0.4818 0.072 Seasonal 2009 vaccination no 0 a . . 0 a . . CMV-serostaus positive 0.163 0.3143 0.605 0.425 0.3732 0.255 CMV-serostaus negative 0 a . . 0 a . . Timepoint 3 1.377 0.2333 < 0.001 1.548 0.3552 < 0.001 Timepoint 2 2.175 0.2797 < 0.001 2.144 0.4236 < 0.001 Timepoint 1 0 a . . 0 a . . CMV-serostatus positive * Timepoint 3 -0.065 0.3074 0.832 -0.278 0.4502 0.537 CMV-serostatus positive * Timepoint 2 0.088 0.3812 0.817 -0.271 0.5373 0.614 CMV-serostatus positive * Timepoint 1 0 a . . 0 a . . CMV-serostatus negative * Timepoint 3 0 a . . 0 a . . CMV-serostatus negative * Timepoint 2 0 a . . 0 a . . CMV-serostatus negative * Timepoint 1 0 a . . 0 a . . Supplementary Table 6. Regression table effect CMV-serostatus on seasonal influenza vaccine response of H3N2 strain in the season 2010-2011. Bold: p value <0.10 Bold and underlined: p value <0.05. a reference category

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