Milea Timbergen

111 Supplemental Figure 2. Supervised hierarchical clustering based on differentially methylated regions (DMRs) between DTF tumour sizes. Tumour sizes were based on initial imaging data obtained at diagnosis. The following size classes were analysed ≤ 34 mm; >35mm ≤ 55 mm; ≥56 mm ≤ 87 mm; > 87 mm. Supplemental Figure 3. Supervised hierarchical clustering based on differentially methylated regions (DMRs) between DTF tumour size extremes. Tumour sizes were based on initial imaging data obtained at diagnosis. The smallest tumours ≤ 34 mm were compared to the largest tumours > 87 mm. 4