Milea Timbergen

131 Table 1. Clinical characteristics of both cohorts. Differential diagnosis cohort Mutation analysis cohort DTF n = 72 Fibro- myxosarcoma n = 64 Leiomyo- sarcoma n = 31 Myxoid liposarcoma n = 36 DTF n = 61 Sex Male Female 16 (22%) 56 (78%) 41 (64%) 23 (36%) 19 (61 %) 12 (39%) 22 (61%) 14 (39%) 15 (25%) 46 (75%) Age median (IQR) 36 (23-47) 67 (54-77) 66 (55-73) 42 (35-56) 36 (22-47) Tumour site Head / neck Chest aperture Abdominal wall Back Intra-abdominal Upper extremity Lower extremity 12 (17%) 4 (6%) 24 (33%) 11 (15%) 1 (1%) 5 (7%) 15 (21%) - - - - - 6 (9%) 58 (91%) - - - - - 7 (23%) 24 (77%) - - - - - 1 (3%) 35 (97 %) 11 (18%) 3 (5%) 16 (26%) 10 (16 %) 1 (2%) 5 (8%) 15 (25%) Tumour size in cm a median (IQR) 6.3 (4.1-9.8) 7.0 (4.9-12.9) 8.3 (5.2-9.4) 12.8 (8.5-15.3) 6.3 (4.1-9.5) Volume in cl median (IQR) 2.0 (0.5-9.8) 5.6 (1.1-34.1) 8.2 (1.7-11.4) 16.8 (5.2-37.4) 2.2 (0.7-9.6) Mutation type T41A S45F Wild-type NA NA NA NA NA NA NA NA NA NA NA NA 24 (39%) 16 (26%) 21 (34%) MRI sequences T2w FS T2w non-FS T1w PC FS T1w PC non-FS 33 (46%) 32 (70%) 49 (70%) 30 (43%) 37 (58%) 37 (64%) 32 (50%) 24 (48%) 15 (48%) 19 (39%) 19 (48%) 11 (23%) 16 (44%) 19 (43%) 22 (51%) 17 (33%) 26 (43%) 26 (61%) 43 (70%) 25 (35%) DTF, desmoid-type fibromatosis; IQR, interquartile range; cm, centimetre; cl, centilitre; MRI, magnetic resonance imaging; FS, FatSat; PC, post-contrast. a maximum diameter automatically measured in three planes. Percentages might not add up to 100% in total because of rounding. 5