Milea Timbergen

208 Supplementary Table 5. Published patient characteristics of the included studies Kim et al. 43 (2016), Oncology Letters Salas et al. 49 (2010), Genes, Chromosomes & Cancer Nishida et al. 42 (2016), Oncology Letters Mullen et al. 20 (2013), The Oncologist Mussi et al. 41 (2016), Tumori Broekhoven et al. 22 (2015), Annals of Surgical Oncology Colombo et al. 23 (2013), Cancer Main study outcome To assess the predictive value CTNNB1 mutation, midkine, B-catenin, TCF-4 and menin in the risk of tumour recurrence Molecular characterization by array CGH To analyse the surgical outcome of patients with extra-peritoneal DTF treated with ST ± surgery To analyse prevalence of CTNNB1 mutations and to determine the correlation between CTNNB1 mutation type and disease outcome To analyse prognostic factors and local disease free survival of abdominal DTF To analyse clinico-pathologic factors and their prognostic significance To test β-catenin as a prognostic marker of aggressiveness Total number of patients 159 194 13 115 33 101 179 Sex Male 77 (48%) 60 (31%) 2 30 (26%) 5 (15%) 35 (35%) 62 (35%) Female 82 (52%) 132 (68%) 11 85 (74%) 28 (5%) 66 (65%) 117 (65%) Unknown - 2 (1%) - - - - - Median age in years / mean age in years [IQR] / (range) 41.2 (7-83) a 32 (0.04–80) b 36 (19-70) b 36 (3-76) b 37 (28-61) b 36 [28-44] c 39 (5-76) b 7