Milea Timbergen

61 Table 1. Patients and tumour characteristics of the Dutch and French cohort. The subgroups includes tumours harbouring a T41A, S45F or a wild-type CTNNB1 mutation Dutch cohort French cohort Total group (n = 64) Subgroup (n = 61) Total group (n = 128) Subgroup (n = 93) Clinicopathological characteristics Number of patients (%) Number of patients (%) Sex Male Female Unknown 23 41 - (35.9%) (64.1%) - 22 39 - (36.1%) (63.9%) - 45 79 4 35.2% 61.7% 3.1% 36 56 1 38.7% 60.2% 1.1% Median age in years at diagnosis (minimum age – maximum age) 35 (4-79 years) 34 (4-79 years) 38 (1-74 years) a 37 (1-73 years) b Mutation type T41A S45F WT Other Unknown 38 12 11 3 - 59.4% 18.8% 17.2% 4.7%* - 38 12 11 - - (62.3%) (19.7%) (18%) - - 45 34 14 12 23 35.2% 26.6% 10.9% 9.4%** 18% 45 34 14 - - (48.4%) (36.6%) (15.1%) Tumour site Extra-abdominal Abdominal wall Intra-abdominal Unknown 38 24 2 - 59.4% 37.5% 3.1% - 38 21 2 - (62.3%) (34.4%) (3.3%) - 86 24 12 6 67.2% 18.8% 9.4% 4.7% 66 20 6 1 (71%) (21.5%) (6.5%) (1.1%) Median tumour size on radiology in mm (minimum size – maximum size 45 (10-135 mm) c 45 (10-135 mm) d 70 (5-300 mm) e 70 (5-300 mm) f a n = 117, n = 11 missing value; b n = 90, n = 3 missing value; c n=47, n = 17 missing value; d n = 44, n = 17 missing value; e n = 107, n = 21 missing value; f n = 84, n = 9 missing value * n = 3 133T>C (S45P); ** n = 6 133T>C (S45P), n = 1 c.113_149delCTAC; n=1 c.132_191del; n = 1 c.133delinsAAGG; n = 1 c.97_102del; n = 1 c.105_107del; n = 1 c.[98C>T(+)99T>G] 3