Carolien Zeetsen

106 A limitation to the study is that not all patients who were admitted to the clinic during data collection could be included. Despite the fact that almost one–third of patients were excluded from the study, we strongly argue that this group does not represent a subsample of patients. As is explained in detail in the Participants section, exclusion was mostly based on the lack of implementation of the MoCA in the first few years of the study, readmission of patients during the study or early discharge against medical advice. The results also showed that the included patients were still representative for the total sample. In summary, this study describes the course of cognitive performance on the MoCA during treatment towards abstinence and recovery, in three patient groups. The study confirms that patients with AUD had the highest MoCA scores, followed by patients with ARCI and those with KS respectively. Surprisingly, all three groups improved significantly over time. It can be concluded that performance on the memory domain is the best predictor for KS: scores were significantly lowest and no improvement occurred in the first six weeks of abstinence and recovery, where patients with AUD and those with ARCI scored higher and improved over the course of treatment. As for everyday cognitive functioning, it was confirmed that patients have a lack of insight into their cognitive deficits, as scores of all three patient groups were comparable while the clinician reports were significantly different between groups. Interestingly, by comparing changes in cognitive performance to changes in everyday cognitive functioning, it was found that especially for patients with KS, changes in overall cognitive performance and on the domain orientation relate positively to changes in everyday cognitive functioning.