Carolien Zeetsen

56 (2005). Third, the extensive gold standard NPA, using widely used, valid and reliable tests, made analysis of specific domains and comparisons between patients with or without NCD possible, which has not been done before in a heterogeneous group of patients with SUD. Fourth, parallel MoCA versions were administered at two time points, which made it possible to assess validity predictively and concurrently. Finally, the effects of substance type and abstinence duration on MoCA performance were taken into account. Although a moderate concurrent validity of the MoCA as compared to the NPA was found, it should be stressed that using a MoCA cut–off score of 25 results in only 66.7% of patients with NCD being classified correctly. Therefore, we underscore the fact that the MoCA as a screen can never substitute an extensive NPA. Therefore, a subsequent extensive NPA is recommended, especially in patients who perform above or at the cut–off point, given the low sensitivity.