Carolien Zeetsen

86 Results Patient characteristics Between June 2010 and March 2019, 796 cases were admitted to the clinic (600 unique patients, as some were readmitted over the years). Of these unique patients, 73.8% were men. The age at admission ranged from 27–86 years, with a mean of 56.6 years ( SD = 8.7). Of all 796 cases, 91 (11.4%) were diagnosed with AUD, 415 (52.1%) with ARCI and 210 (26.4%) with KS. In the remaining 80 cases (‘other’; 10.1%), 57 were undiagnosed for various reasons, mostly due to leaving the clinic early against medical advice, and another 23 patients had a diagnosis other than AUD, ARCI or KS (i.e. a neurodegenerative disorder [ n = 10], non–alcohol or polysubstance use disorder [ n = 5], NCD not due to a substance [ n = 4], psychotic disorder [ n = 2] and depression [ n = 2]). Comparisons between these four groups revealed no significant differences for sex distribution, level of education (classified as described by Bruijnen, Jansen, et al., 2019) and abstinence duration at MoCA administration. We found that patients with KS were significantly older than both patients with AUD and those with ARCI. Duration of admission was shortest for the ‘other’ patients, followed by patients with AUD, ARCI and KS, respectively. Patients with ARCI were significantly more often readmitted to this clinic than all other patient groups (Table 5.1). Furthermore, in 232 of all 796 cases the MoCA was not administered, most probably accounted for by: 1) no diagnosis or a diagnosis other than AUD, ARCI or KS ; 2) MoCA administration being limited to version 7.1 in the first two years of data collection and not being immediately implemented in treatment as usual by all professionals (assessment of MoCA versions 7.2 and 7.3 was introduced in March 2012 and July 2013, respectively); 3) patients being readmitted to the clinic did not complete the MoCA again if they already completed all three versions in their previous admission, 4) patients not being motivated to complete the MoCA assessment; and 5) inability to administer the MoCA due to physical limitations or insufficient Dutch language skills. In the following analyses, only patients with a diagnosis of AUD, ARCI or KS, and at least one MoCA administration were included, to comprise our total sample of 524 patients. Of these, 71 were diagnosed with AUD, 284 with ARCI and 169 with KS. The other 272 patients were excluded. To rule out possible selection bias between the included and excluded cases in terms of demographic characteristics and severity of cognitive impairments, they were statistically compared to the included patients. The distribution of patients between diagnostic groups was unequal, where proportionately more patients with ARCI were excluded, while proportionately more patients with KS were included ( χ 2 (2, n = 716) = 11.55, p = .003). There were no differences in age, sex,

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