Els van de Vijver

11 Table 1: Knowledge gaps concerning paediatric IBD Diagnostics Appropriate triage for patients with gastrointestinal complaints for endoscopic evaluation Reliable monitoring of disease activity in ambulatory patients Treatment Understanding the effect of enteral nutrition on inflammation (and predicting success/failure) Comparison between novel and currently available medication for children: long-term safety and efficacy Use of genetic profiling to develop precision medicine Effect of altering the gut microbiome with anti/pro/prebiotics Education of patients Optimizing drug adherence Achieving treatment self-competence and autonomy in adolescents Improving quality of life Supporting psychological growth Physical and psychological impact of lifelong therapy Quantification and characterisation of fatigue in IBD Identifying factors associated with fatigue Inflammatory bowel disease is a chronic illness that is frequently characterized by periods of exacerbation and remission, and that often follows a progressive course. Unpredictable flares, frequent hospitalizations and chronic medication use affect psychosocial functioning and limit social activities.(4) Early recognition of IBD can reduce the inflammation in an early General introduction