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124 18. Minderhoud IM, Oldenburg B, van Dam PS, van Berge Henegouwen GP. High prevalence of fatigue in quiescent inflammatory bowel disease is not related to adrenocortical insufficiency. Am J Gastroenterol. 2003;98(5):1088-93. 19. Jelsness-Jorgensen LP, Bernklev T, Henriksen M, Torp R, Moum BA. Chronic fatigue is associated with impaired health-related quality of life in inflammatory bowel disease. Aliment Pharmacol Ther. 2011;33(1):106-14. 20. Grimstad T, Norheim KB, Kvaloy JT, Isaksen K, Leitao K, Carlsen A, et al. Conventional treatment regimens for ulcerative colitis alleviate fatigue - an observational cohort study. Scand J Gastroenterol. 2016;51(10):1213-9. 21. Loftus EV, Feagan BG, Colombel JF, Rubin DT, Wu EQ, Yu AP, et al. Effects of adalimumab maintenance therapy on health-related quality of life of patients with Crohn's disease: patient- reported outcomes of the CHARM trial. Am J Gastroenterol. 2008;103(12):3132-41. 22. Nocerino A, Nguyen A, Agrawal M, Mone A, Lakhani K, Swaminath A. Fatigue in Inflammatory Bowel Diseases: Etiologies and Management. Adv Ther. 2020;37(1):97-112. 23. Tojek TM, Lumley MA, Corlis M, Ondersma S, Tolia V. Maternal correlates of health status in adolescents with inflammatory bowel disease. J Psychosom Res. 2002;52(3):173-9. 24. Ondersma SJ, Lumley MA, Corlis ME, Tojek TM, Tolia V. Adolescents with inflammatory bowel disease: the roles of negative affectivity and hostility in subjective versus objective health. J Pediatr Psychol. 1997;22(5):723-38. 25. Farrell D, Artom M, Czuber-Dochan W, Jelsness-Jorgensen LP, Norton C, Savage E. Interventions for fatigue in inflammatory bowel disease. Cochrane Database Syst Rev. 2020;4:Cd012005. 26. Stapersma L, van den Brink G, van der Ende J, Szigethy EM, Groeneweg M, de Bruijne FH, et al. Psychological Outcomes of a Cognitive Behavioral Therapy for Youth with Inflammatory Bowel Disease: Results of the HAPPY-IBD Randomized Controlled Trial at 6- and 12-Month Follow-Up. J Clin Psychol Med Settings. 2019. 27. Loonen HJ, Grootenhuis MA, Last BF, de Haan RJ, Bouquet J, Derkx BH. Measuring quality of life in children with inflammatory bowel disease: the impact-II (NL). Qual Life Res. 2002;11(1):47- 56. 28. Werkstetter KJ, Ullrich J, Schatz SB, Prell C, Koletzko B, Koletzko S. Lean body mass, physical activity and quality of life in paediatric patients with inflammatory bowel disease and in healthy controls. J Crohns Colitis. 2012;6(6):665-73. 29. Houborg KB, Jensen MB, Rasmussen P, Gandrup P, Schroll M, Laurberg S. Postoperative physical training following colorectal surgery: a randomised, placebo-controlled study. Scand J Surg. 2006;95(1):17-22. Chapter 7 124

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