Els van de Vijver
27 Table 1: Patient characteristics Confirmed IBD (n=42) Non-IBD (n=75) Age in years, mean (SD; range) 14 (3,3; 6-18) 12,9 (3,8; 6-18) Male (%) 45 50 Presenting Symptoms (% (95% CI)) Rectal blood loss 62% (47 to 77) 41% (30 to 52) Unintended weight loss or linear growth retardation 55% (40 to 70)) 46% (35 to 57) Peri-anal symptoms (skin tag, fistula, fissure, abscess) 19% (7 to 31) 9% (3 to 15) Anaemia: < 12 y: 7.1; girls ≥ 12 y: 7.4; boys ≥ 12 y: 8.1 (Hb cut-point in mmol/L) or other extra-intestinal manifestations (erythema nodosum, arthritis, uveitis)* 83% (72 to 94) 46% (35 to 57) Increased markers of inflammation: ESR > 20 mm/hr; Creactive protein > 10 mg/L * 83% (72 to 94) 28% (18 to 38) * p < 0.05 IBD was confirmed in 42 patients (36%). Twenty-four were diagnosed with Crohn’s disease, 16 with ulcerative colitis and two with IBD unclassified. There were no differences in age and sex between the groups with confirmed IBD and non-IBD. The paediatricians, who were blinded to the faecal calprotectin result, referred 68 children and teenagers for endoscopy on the basis of a high index of suspicion for IBD. They were evaluated according to the Porto criteria with gastroscopy and ileocolonoscopy (97% ileal intubation) with segmental biopsies for histological evaluation. One child was diagnosed with Crohn’s Disease after a negative gastroscopy and ileocolonoscopy but positive MR enterography. Ruling out IBD without referral for endoscopy
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