Els van de Vijver

42 Figure 1 I Algorithm explaining the multi-step IBD Risk Stratifier used to standardize the assignment of patients to either endoscopy or clinical follow-up Paediatricians could deviate from this advice for documented clinical reasons. Endoscopy was performed under general anesthesia by an experienced paediatric gastroenterologist in one of six participating centers. Both upper and lower gastrointestinal tract were evaluated according to the revised Porto criteria,(14) and biopsies were taken from every bowel segment. Histopathological examination was performed by experienced histopathologists. Endoscopists and histopathologists had access to clinical information and calprotectin results, Chapter 3