Adriëtte Oostvogels

4 107 Maternal lipids and offspring’s lipids & glucose significance. All analyses were conducted with the SPSS version 21.0 and R package version 3.0.3. A p-value of <0.05 was considered statistically significant. Results Study population The final study population consisted of 1133 mother-child pairs predominantly of Dutch origin (73%). Mean (SD) maternal age during pregnancy was 32.3 (4.2) years and mean (SD) pBMI 22.8 (3.6) kg/m 2 . Their children (49% boys) were on average 5.7 years at the health check. Compared to the non-response group, mothers included in this study were more often of Dutch origin, multiparous and smoked and drank alcohol more often during pregnancy and breastfed their children longer (Supplementary table 1). Compared with girls (n=573), boys (n=560) had mothers with slightly higher TC, ApoB and FFA levels, and had higher glucose, but lower TC, LDL and TG levels themselves. Moreover, boys had a slightly higher intake of saturated fat and fibre, and spent more time looking at screens (Table 1). Table 1. Characteristics of the participants (mother and child) divided into the sex of the offspring (total=1133). Boys (n=560) Girls (n=573) N/ mean %/SD N/ mean %/SD Maternal characteristics Age (years) 32.3 4.2 32.3 4.1 Body mass index (kg/m 2 ) 22.8 3.5 23.0 3.7 Ethnicity Dutch 398 71.1 425 74.2 Turkish 14 2.5 10 1.7 Moroccan 29 5.2 16 2.8 Non-western 41 7.3 55 9.6 Western 78 13.9 67 11.7 Education after primary school (years) 10.2 3.6 10.3 3.4 Parity (Primiparous) 313 55.9 318 55.5 Hypertension none 508 90.7 496 86.6 pre-existent 13 2.3 19 3.3 pregnancy-induced 39 7.0 58 10.1