Adriëtte Oostvogels

110 Chapter 4 Offspring’s lipids TC (mmol/l) HDL (mmol/l) LDL (mmol/l) Ln(TG) (mmol/l) Maternal lipids β 95%CI β 95%CI β 95%CI β 95%CI TC (mmol/l) boy (n=543) M1 a 0.140 0.075-0.205*** 0.028 -0.004-0.059 0.119 0.058-0.179*** 0.028 -0.017-0.073 M2 b 0.141 0.074-0.207*** 0.025 -0.008-0.057 0.115 0.053-0.177*** 0.016 -0.030-0.063 M3 c 0.141 0.074-0.207*** 0.025 -0 .007-0.058 0.114 0 .052-0.176*** 0.015 -0.031-0.062 girl (n=561) M1 0.266 0.200-0.332*** 0.010 -0.021-0.042 0.252 0.189-0.315*** 0.062 0.022-0.102** M2 0.268 0.200-0.336*** 0.017 -0.015-0.048 0.247 0.181-0.312*** 0.057 0.016-0.099** M3 0.268 0.200-0.336*** 0.017 -0.015-0.048 0.247 0.181-0.312*** 0.057 0.015-0.098** ApoA1 (g/l) boy (n=517) M1 0.152 -0.097-0.401 0.234 0.117-0.350*** -0.027 -0.261-0.206 -0.080 -0.250-0.091 M2 0.096 -0.158-0.349 0.219 0.099-0.339*** -0.086 -0.324-0.151 -0.088 -0.261-0.086 M3 0.094 -1.160-0.347 0.221 0.101-0.341*** -0.091 -0.328-0.146 -0.092 -0.265-0.081 girl (n=548) M1 0.368 0.107-0.630** 0.083 -0.037-0.203 0.191 -0.056-0.437 0.257 0.102-0.412** M2 0.313 0.041-0.586* 0.106 -0.017-0.229 0.106 -0.151-0.364 0.218 0.058-0.378** M3 0.313 0.040-0.586* 0.106 -0.017-0.229 0.106 -0.151-0.364 0.218 0.058-0.378** ApoB (g/l) boy (n=524) M1 0.516 0.200-0.833** -0.086 -0.239-0.066 0.632 0.337-0.928*** 0.219 <0.001-0.438* M2 0.641 0.314-0.967*** -0.076 -0.236-0.084 0.709 0.403-1.015*** 0.170 -0.057-0.397 M3 0.638 0.311-0.965*** -0.071 -0.231-0.089 0.699 0.393-1.005*** 0.159 -0.068-0.385 girl (n=550) M1 1.050 0.710-1.390*** -0.084 -0.244-0.076 1.132 0.816-1.449*** 0.248 0.040-0.456* M2 1.121 0.767-1.475*** -0.066 -0.231-0.100 1.198 0.868-1.528*** 0.251 0.035-0.467* M3 1.121 0.766-1.475*** -0.066 -0.232-0.100 1.198 0.868-1.529*** 0.251 0.035-0.467* TG (mmol/l) boy (n=543) M1 -0.013 -0.122-0.096 -0.042 -0.094-0.010 0.016 -0.085-0.117 0.095 0.021-0.169* M2 0.002 -0.111-0.116 -0.050 -0.105-0.005 0.031 -0.074-0.137 0.097 0.020-0.174* M3 0.003 -0.111-0.116 -0.048 -0.103-0.006 0.030 -0.076-0.135 0.095 0.018-0.172* Table 2. Linear regression model of the association between maternal early pregnancy lipids and offspring’s lipids at age 5-6 years.