Adriëtte Oostvogels

5 125 Family history of diabetes and childhood outcomes Family history of diabetes mellitus Maternal only, paternal only or both maternal and paternal FHD in second-degree relatives was based on self-reported data in the 5-6 years questionnaire in which the mother was asked whether any of her parents and/or siblings had diabetes and whether any of the parents and/or siblings of the biological father of the child had diabetes. FHD in second-degree relatives was divided into four distinctive groups: no FHD (n=2,226), maternal (n=353), paternal (n=281) or both maternal and paternal (n=164) FHD. Outcome measurements Outcomes were measured at the ABCD health check at a mean age of 5.7 years (SD=0.5). BMI and WHtR were computed from weight measured to the nearest 100 g using a Marsden MS-4102 weighing scale (Oxfordshire, United Kingdom); waist circumference measured midway between the costal border and the iliac crest to the nearest millimetre using a Seca measuring tape; and height measured to the Figure 1. Flowchart of the study population of the ABCD-study