Adriëtte Oostvogels

5 No FHD (ref) N=1574 Maternal FHD only N=210 Paternal FHD only N=186 Maternal + Paternal FHD N=63 Mean (SD) / % Mean (SD) / % Mean (SD) / % Mean (SD) / % Maternal/Paternal characteristics Maternal age (years) 32.7 (3.8) 32.6 (4.2) 32.7 (3.8) 32.8 (5.1) Maternal education (years after primary school) 10.9 (2.9) 10.4 (3.0) 10.5 (3.1) 9.8 (2.8)* Maternal body mass index (kg/m 2 ) when offspring were 5 years old 22.8 (3.3) 23.8 (4.3)* 23.4 (3.5) 23.9 (4.0) Paternal body mass index (kg/m 2 ) when offspring were 5 years old 24.5 (2.7) 24.6 (2.8) 25.4 (3.1)* 26.1 (3.4)* Child’s characteristics Gestational age at birth (days) 280 (11) 278 (13)* 278 (14)* 279 (13) Birth weight (g) 3536 (511) 3482 (576) 3413 (627)* 3505 (694) Age at measurements (years) 5.7 (0.5) 5.6 (0.4) 5.7 (0.5) 5.7 (0.5) Sex – % Boys 49.7 54.8 55.9 55.6 Screen time (hours/day) 1.2 (0.7) 1.4 (0.8)* 1.3 (0.8) 1.3 (0.9) Energy intake (kcal/day) 1513 (294) 1479 (275) 1539 (302) 1580 (414) Supplementary Table 2. Characteristics of Dutch study population only (N=2033) compared between groups of second-degree family history of diabetes (FHD) within the ABCD-study * p<0.05 significantly different from the no second-degree family history category 141 Family history of diabetes and childhood outcomes

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