Adriëtte Oostvogels

88 Chapter 3 Child WHtR*100 Fat percentage (%) BMI (kg/m 2 ) Risk for overweight Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Maternal lipids β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) β (95% CI) OR (95% CI) OR (95% CI) TC (mmol/L) 0.13 (20.02; 0.28) 0.11 (20.04; 0.26) 0.50 (0.18; 0.81) 0.47 (0.16; 0.79) 0.08 (20.00; 0.15) 0.08 (20.00; 0.15) 1.20 (1.00; 1.45) 1.17 (0.97; 1.42) ApoA1 (g/L) 20.01 (20.63; 0.61) 0.02 (20.60; 0.63) 0.31 (20.96; 1.59) 0.89 (20.37; 2.15) 20.07 (20.38; 0.24) 0.09 (20.23; 0.40) 0.77 (0.34; 1.74) 1.14 (0.49; 2.63) ApoB (g/L) 0.87 (0.09; 1.65) 0.57 (20.21; 1.35) 3.19 (1.58; 4.79) 2.02 (0.44; 3.59) 0.45 (0.06; 0.84) 0.28 (20.11; 0.67) 3.25 (1.25; 8.44) 2.00 (0.73; 5.49) Ratio ApoB/ApoA 1.20 (0.14; 2.26) 0.80 (20.26; 1.86) 3.64 (1.46; 5.83) 1.69 (20.46;3.85) 0.59 (0.06; 1.12) 0.23 (20.30; 0.76) 4.85 (1.38; 17.07) 1.92 (0.50; 7.42) TG (mmol/L) 0.48 (0.23; 0.74) 0.31 (0.06; 0.57) 0.83 (0.30; 1.36) 0.36 (20.17; 0.89) 0.19 (0.06; 0.32) 0.12 (20.01; 0.25) 1.48 (1.10; 1.99) 1.24 (0.91; 1.68) FFA (mmol/L) 1.09 (0.27; 1.91) 0.83 (20.001; 1.65) 3.28 (1.58; 4.98) 2.02 (0.33; 3.71) 0.68 (0.27; 1.09) 0.45 (0.03; 0.86) 4.88 (1.94; 12.31) 3.06 (1.13; 8.30) Table 3. Association between maternal lipids and childhood adiposity (n = 1727). WHtR; weight to height ratio, TC; total cholesterol, ApoA1; apolipoprotein A1, ApoB; apolipoprotein B, TG; triglyceride, FFA; free fatty acids. Model 1: Adjusted for gestational age at blood sampling, age of the child, sex. Model 2: As model 1 with additional adjustment for age of mother, parity, ethnicity, height, years of education, alcohol, smoking, and hypertension and from the child: duration of exclusive breastfeeding, screen time hours/day and saturated fat intake.