Enrico Martin

18 Chapter 1 likely high in MPNSTs, but functional reconstructions seem uncommonly used, we will investigate current attitudes of surgeons towards incorporating function preservation in MPNSTs in Chapter 10 . Differences in attitude between surgical subspecialties will therefore be assessed in specific. Finally, an international collaboration among several surgical subspecialties was set up for this thesis including 10 Dutch cancer centers and the Mayo Clinic in Rochester to retrospectively collect data on both oncological and functional outcomes in MPNSTs (the MONACO study). In Chapter 11 we will use data acquired in the MONACO study to investigate the prevalence of postoperative motor and critical sensory loss, patients at high risk for postoperative morbidity, and the use and outcomes of functional reconstructions in MPNST.