Enrico Martin

201 Functional reconstructions in extremity STS defects being reconstructed and the diversity in outcome measures used. Also, with only a small amount of cases with differing tumor grades, location, and indications for multimodal treatment may have differed. As such, investigating the correlation of multimodal treatment to functional outcomes is impaired. Nonetheless, this study shows encouraging outcomes for the use of functional reconstructions. These results may stimulate sarcoma teams to incorporate early participation of experienced reconstructive plastic surgeons and rehabilitation teams. Such cooperation may result in facilitating wider tumor excision as well as planned preservation of certain structures needed for reconstruction. In order to increase our understanding of outcomes, future studies on limb salvage in STS patients should preferably differentiate functional reconstructions from soft-tissue coverage only. Additionally, when investigating outcomes of functional reconstructions, future studies are to be stimulated using both objective outcome measures assessing true muscle or sensory function and subjective outcome measures. This may further help elucidate expected outcomes and select ideal candidates. As such, sarcoma teams will increasingly be capable to incorporate functional reconstructions as part of their treatment strategy in extremity STS. Conclusion Functional reconstructions in extremity STS are uncommon in literature. However, resection of major nerves or complete muscle groups can lead to loss of specific functions. Reconstructions of nerves, muscles, and tendons can potentially improve function. As numerous options exist, the choice of reconstruction depends mainly on patient and tumor characteristics, such as size and location. Multimodal treatment does however not preclude successful restoration of function. A patient-tailored approach is needed to balance appropriate oncological resections with optimal functional outcome. 8