Enrico Martin

258 Chapter 11 Table 1 Patient characteristics and presenting symptoms of all patients. Variable Overall N 756 Age (years) 0-18 72 (9.5%) 19-60 512 (67.7%) 60+ 172 (22.8%) Mean (SD) 44.3 (±19.4) Male gender 400 (53.0%) MPNST Sporadic 441 (58.3%) NF1 253 (33.4%) Radiation-induced 62 (8.2%) Tumor site Extremities 286 (37.8%) Brachial plexus 52 (6.9%) Head and neck 92 (12.2%) Pelvic 68 (9.0%) Core 248 (32.8%) Unknown 10 (1.3%) Major nerve of origin Any 260 (34.4%) Motor 15 (4.1%) Mixed 190 (80.7%) Sensory 51 (15.2%) Tumor size <5cm 155 (27.0%) 5-10cm 221 (36.3%) ≥10cm 191 (36.7%) NA 189 Mean (SD) 8.6cm (±5.6) Tumor depth Superficial 83 (18.2%) Deep 373 (81.8%) NA 25 Synchronous metastasis 99 (13.4%) Symptoms at diagnosis Mass 273 (56.8%) Pain 349 (48.8%) Motor deficit 114 (15.8%) Sensory deficit 101 (13.4%) Other 94 (13.4%) NA 72 Multiple symptoms 1 symptom 350 (58.5%) 2 symptoms 169 (28.3%) >2 symptoms 79 (13.2%) NA 158 N: number of patients, NA: not available, NF1: neurofibromatosis type 1, SD: standard deviation