Enrico Martin

30 Chapter 2 Table 1 Demographical differences between tumor sites. Variable Definition Total Intracranial Spinal H&N Limbs Core NOS & Unknown P Number of patients 3267 167 119 449 1022 1307 203 Age <18 282 (8.6) 10 (6.0) 9 (7.6) 47 (10.5) 90 (8.8) 104 (8.0) 22 (10.8) <0.001 19-59 1970 (60.3) 105 (62.9) 67 56.3) 228 (50.8) 662 (64.8) 791 (60.5) 117 (57.6) 60+ 1015 (31.1) 52 (31.1) 43 (36.1) 174 (38.8) 270 (26.4) 412 (31.5) 64 (31.5) Mean (SD) 47.6 (21.0) 50.9 (20.1) 49.1 (21.7) 51.1 (22.5) 45.5 (20.8) 47.5 (20.3) 47.3 (21.9) Sex Female 1501 (45.9) 83 (49.7) 51 (42.9) 180 40.1) 478 (46.8) 619 (47.4) 90 (44.3) 0.103 Male 1766 (54.1) 84 (50.3) 68 (57.1) 269 (59.9) 544 (53.2) 688 (52.6) 113 (55.7) Race White 2579 (78.9) 144 (86.2) 93 (78.2) 365 (81.3) 786 (76.9) 1020 (78.0) 171 (84.2) 0.001 Black 417 (12.8) 16 (9.6) 12 (10.1) 45 (10.0) 163 (15.9) 163 (12.5) 18 (8.9) Asian & other 253 (7.7) 5 (3.0) 13 (10.9) 38 (8.5) 64 (6.3) 119 (9.1) 14 (6.9) Unknown 18 (0.6) 2 (1.2) 1 (0.8) 1 (0.2) 9 (0.9) 5 (0.4) 0 (0.0) Treatment Sx only 1528 (46.8) 64 (38.3) 61 (51.3) 204 (45.4) 501 (49.0) 620 (47.4) 78 (38.4) <0.001 RTx only 144 (4.4) 24 (14.4) 5 (4.2) 15 (3.3) 19 (1.9) 73 (5.6) 8 (3.9) Sx and RTx 1070 (32.8) 30 (18.0) 39 (32.8) 165 (36.7) 405 (39.6) 388 (29.7) 43 (21.2) None 300 (9.2) 30 (18.0) 9 (7.6) 39 (8.7) 43 (4.2) 133 (10.2) 46 (22.7) Unknown 225 (6.9) 19 (11.4) 5 (4.2) 26 (5.8) 54 (5.3) 93 (7.1) 28 (13.8) Tumor Grade I 157 (4.8) 0 (0.0) 2 (1.7) 25 (5.6) 60 (5.9) 64 (4.9) 6 (3.0) <0.001 II 391 (12.0) 5 (3.0) 4 (3.4) 71 (15.8) 154 (15.1) 141 (10.8) 16 (7.9) III 411 (12.6) 4 (2.4) 4 (3.4) 42 (9.4) 172 (16.8) 167 (12.8) 22 (10.8) IV 549 (16.8) 8 (4.8) 9 (7.6) 62 (13.8) 216 (21.1) 240 (18.4) 14 (6.9) Unknown 1759 (53.8) 150 (89.8) 100 (84.0) 249 (55.5) 420 (41.1) 695 (53.2) 145 (71.4) Tumor Size ≤50 mm 798 (24.4) 61 (36.5) 32 (26.9) 171 (38.1) 265 (25.9) 254 (19.4) 15 (7.4) <0.001 >50 mm 1283 (39.3) 15 (9.0) 14 (11.8) 91 (20.3) 482 (47.2) 625 (47.8) 56 (27.6) Unknown 1186 (36.3) 91 (54.5) 73 (61.3) 187 (41.6) 275 (26.9) 428 (32.7) 132 (65.0) Median (mm) 67.0 37.4 39.5 38.0 70.0 80.0 88.0 IQR (mm) 37.0-100.0 17.3-43.5 20.0-60.0 20.0-65.0 40.0-100.0 50.0-115.0 60.0-130.0 GTR: gross total resection, IQR: interquartile range, mm: millimeters, NOS: not otherwise specified, SD: standard deviation