Enrico Martin

33 Treatment and survival differences across tumor sites tumors were independently associated with superior survival (both p<0.05, Table 3 and 4 ). MPNSTs originating from the head and neck or core sites showed significantly poorer survival (both p<0.05). Also, older age, male sex, black race, higher tumor grade (grade III and IV), and large tumor size were independently prognostic for worse survival (all p<0.05). Patients that did not receive surgical treatment or only a biopsy were significantly associated with worse survival ( Table 4 ). The sequence of radiotherapy did not have any influence on the survival of patients ( Table 4 ), nor did any addition of radiotherapy to surgery (all p>0.05, Table 3 ). After applying a Bonferroni correction to all three models, only large tumor size, high tumor grades, core site, and treatment modalities without surgery significantly reduced overall survival (all p<0.002). 2

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