Enrico Martin

46 Chapter 2 Supplemental Table 4 Univariate Cox analyses of overall survival in limbs, core, and NOS & unknown tumor sites Variable Definition Limbs HR (95% CI) P Core HR (95% CI) P NOS & Unknown HR (95%CI) P Age 19-59 Ref. Ref. Ref. <18 0.92 (0.66-1.30) 0.648 0.78 (0.59-1.05) 0.097 0.82 (0.43-1.56) 0.545 60+ 1.96 (1.60-2.41) <0.001 1.41 (1.20-1.65) <0.001 1.59 (1.06-2.37) 0.024 Sex Female Ref. Ref. Ref. Male 1.16 (0.96-1.40) 0.132 1.16 (1.01-1.35) 0.042 1.27 (0.88-1.85) 0.208 Race White Ref. Ref. Ref. Black 1.22 (0.95-1.56) 0.125 1.17 (0.95-1.45) 0.142 1.90 (1.06-3.40) 0.031 Asian & other 0.98 (0.66-1.44) 0.899 1.03 (0.80-1.32) 0.840 0.62 (0.27-1.42) 0.262 Unknown 0.70 (0.22-2.17) 0.530 NA NA NA NA Therapy Sx only Ref. Ref. Ref. RTx only 3.00 (1.67-5.38) <0.001 2.74 (2.04-3.68) <0.001 4.29 (1.85-9.94) 0.001 Sx and RTx 1.17 (0.95-1.43) 0.131 1.04 (0.87-1.23) 0.681 1.66 (1.03-2.67) 0.038 None 2.21 (1.44-3.41) <0.001 1.88 (1.45-2.43) <0.001 1.00 (0.58-1.74) 0.997 Unknown 1.46 (0.95-2.23) 0.083 1.90 (1.45-2.48) <0.001 2.66 (1.54-4.59) <0.001 Surgery GTR Ref. Ref. Ref. PR 0.91 (0.72-1.16) 0.438 0.94 (0.76-1.17) 0.588 1.04 (0.54-2.03) 0.899 Biopsy 1.73 (0.71-4.23) 0.231 1.23 (0.82-1.86) 0.315 2.64 (0.88-7.91) 0.083 No Sx 2.19 (1.48-3.24) <0.001 2.56 (1.99-3.31) <0.001 0.94 (0.50-1.76) 0.849 Sx NOS 0.95 (0.73-1.23) 0.681 1.00 (0.81-1.24) 0.968 1.10 (0.62-1.96) 0.749 Unknown 0.66 (0.29-1.51) 0.324 2.72 (2.00-3.70) <0.001 2.35 (1.19-4.65) 0.014