Enrico Martin

CONTENTS Chapter 1 General introduction and thesis outline 11 Part I Oncological Outcomes and Treatment of MPNST Chapter 2 Treatment and survival differences across tumor sites in malignant peripheral nerve sheath tumors: a SEER database analysis and review of the literature Neuro-Oncology Practice (2019) 25 Chapter 3 A nationwide cohort study on treatment and survival in patients with malignant peripheral nerve sheath tumors European Journal of Cancer (2020) 49 Chapter 4 Neurofibromatosis-associated malignant peripheral nerve sheath tumors in children have a worse prognosis: a nationwide cohort study Pediatric Blood & Cancer (2020) 69 Chapter 5 Oncological treatment considerations differ across surgical subspecialties treating malignant peripheral nerve sheath tumors: an international survey Sarcoma (2020) 87 Chapter 6 A Bayesian approach for diagnostic accuracy of malignant peripheral nerve sheath tumors: a systematic review and meta-analysis Submitted 111 Chapter 7 Non-cytotoxic systemic treatment in malignant peripheral nerve sheath tumors (MPNST): a systematic review from bench to bedside Critical Reviews in Oncology/Hematology (2019) 157 Part II Functional Outcomes and Possibilities for Treatment in MPNST Chapter 8 Resuscitating extremities after soft tissue sarcoma resections: are functional reconstructions an overlooked option in limb salvage? A systematic review European Journal of Surgical Oncology (2019) 187

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