Klaske van Sluis

Interaction of functional and participation issues on quality of life 97 Clustering of related self-reported participation and functional issues ques- tions was performed into the following general issue themes (see Appendix A for an overview of the grouped questionnaire questions per theme): • Esthetic issues (5 yes-no questions) • Experienced limitations in daily activities (9 yes-no questions) • Avoiding social activities (2 yes-no questions) • Communication issues (4 yes-no questions) • Experienced vulnerability due to environmental factors (7 yes-no ques- tions) • Pulmonary issues (14 yes-no questions) • Sleep issues (3 yes-no questions) 6.2.5 Average number of reported experienced issues per theme The average number of reported issues per patient per theme (as a percentage of the maximum number of questions of that theme), and the influence of the grouping of respondents on the number of reported experienced issues is presented. This approach was chosen in order to make the themes mutually comparable on the basis of seriousness, since the average weight per issue is not linear and the number and content of issue questions per theme were different.